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Range Overview References

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  1. Bianco L, et al. Pilot randomized controlled dosing study of cranberry capsules for reduction of bacteriuria plus pyuria in female nursing home residents. JAGS. 2012; 60(6):1180-1.
  2. Howell AB, et al. Dosage effect on uropathogenic Escherichia coli antiadhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. BMC Infect Dis. 2010;10(1):94.
  3. Botto H, et al. Effectiveness of a cranberry (Vaccinium macrocarpon) preparation in reducing asymptomatic bacteriuria in patients with an ileal enterocystoplasty. Scand J Urol Nephrol. 2010;44(3):165-168.
  4. Lavigne J, et al. In-vitro and in-vivo evidence of dose-dependent decrease of uropathogenic Escherichia coli virulence after consumption of commercial Vaccinium macrocarpon (cranberry) capsules. Clin Microbiol Infect. 2008;14:350-355.
  5. Uberos J, et al. Cranberry syrup vs trimethoprim in the prophylaxis of recurrent urinary tract infections among children: a controlled trial. Open Access J Clin Trials 2012;4:31-386.
  6. Schellenberg R, et al. Dose-dependent effects of the Cimicifuga racemosa extract Ze 450 in the treatment of climacteric complaints: a randomized, placebo-controlled study. Evid Based Complement Alternat Med. 2012;(1):article ID 2603101.
  7. Drewe J, et al. The effect of a Cimicifuga racemosa extract Ze 450 in the treatment of climacteric complaints – an observational study. Phytomedicine. 2013;15(20):659–666.
  8. Lopatka L, et al. Black cohosh in the treatment of menopausal symptoms-results of an observational study with Cimifemin® uno (English translation) J für Menopause. 2007;2:3-7.
  9. Wesnes KA, et al. The cognitive, subjective, and physical effects of a Ginkgo biloba/Panax ginseng combination in healthy volunteers with neurasthenic complaints. Psychopharmacol Bull. 1997;33(4):677-683.
  10. Wesnes KA, et al. The memory enhancing effects of a Ginkgo biloba/Panax ginseng combination in healthy middle-aged volunteers. Psychopharmacology. 2000:152(4):353-361.
  11. Scholey AB, et al. Acute, dose-dependent cognitive effects of Ginkgo biloba, Panax ginseng and their combination in healthy young volunteers: differential interactions with cognitive demand. Hum Psychopharmacol Clin Exp. 2002;17:35-44.
  12. Reay JL, et al. Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity. Journal of
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  16. Forgo I, et al. Effect of a standardized ginseng extract on general well-being, reaction capacity, pulmonary function and gonadal hormones. Med Welt. 1981;32(19):751-756.
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  18. Scaglione F, et al. Efficacy and safety of the standardized Ginseng extract G115 for potentiating vaccination against the influenza syndrome and protection against the common cold. Drugs Exp Clin Res.1996; 1996;22 (2):65-72.
  19. Reay JL, et al. Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity’ J Psychopharmacol. 2005;19(4):357-365.
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  21. Ginseng: ginseng radix. European Pharmacopoeia 5.1.2005, 2935-2936. 9. Ginseng radix: ginseng. ESCOP Monographs: the Scientific Foundation for Herbal Medicinal Products, 2nd Edition, Exeter, ESCOP, 2003; 211-222 [S05-0651].
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  25. Stough C, et al. Examining the nootropic effects of a special extract of Bacopa monnieri on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial. Phytother Res. 2008;22(12):1629-1634.
  26. Downey L, et al. An acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of Bacopa monnieri (CDRI 08) on sustained cognitive performance. Phytother Res. 2013;27(9):1407-13.
  27. Benson S, et al. An acute, double-blind, placebo-controlled cross-over study of 320 mg and 640 mg doses of Bacopa monnieri (CDRI 08) on multitasking stress reactivity and mood. Phytother Res. 2014;28(4):551-9.
  28. Singh.HK. The Memory-Enhancing and Associated Effects of a Bacosides-Enriched Standardized Extract of Bacopa monniera (BESEB—CDRI-08). In Stough C. & Scholey A. (Eds.) 2013. Advances in Natural Medicines, Nutraceuticals and Neurocognition. Boca Raton: CRC Press, https://doi.org/10.1201/b13736.
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  30. Dehmlow C, et al. Inhibition of Kupffer cell functions as an explanation for the hepatoprotective properties of silibinin. Hepatology. 1996;23(4):749-54.
  31. Trappoliere M, et al. Silybin, a component of sylimarin, exerts anti-inflammatory and anti-fibrogenic effects on human hepatic stellate cells. Journal of hepatology. 2009;50(6):1102-11.
  32. Velussi M, et al. Long-term (23 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. Journal of hepatology. 1997;26(4):871-9.
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  35. Buturova LI, Tsibizova TA 2010, Kalinin AV, Potential for the use of Legalon® in non-alcoholic fatty liver disease, Experimental and Clinical Gastroenterology, no. 3, pp. 85-91.
  36. Zhong S, Fan Y, Yan Q, Fan X, Wu B, et al. 2017, The Therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease: A meta-analysis (PRISMA) of randomized control trials, Medicine (Baltimore), vol. 96, no. 49, pp 1-7.
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  38. Muzes G, Deak G, Lang I, Nekam K, Niederland V & Feher J 1990, Effects of Silybum (Legalon®) Treatment on the Antioxidant Defence System and Lipid Peroxidation in Patients with Chronic Alcohol Liver disease (A Double-Blind Study), Orvosi Hetilap,vol. 131, no. 16.
  39. Schellenberg R, et al. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo controlled study. BMJ. 2001;322:134–7
  40. Schellenberg R, et al. Dose-dependent efficacy of the Vitex agnus-castus extract Ze 440 in patients suffering from premenstrual syndrome. Phytomedicine. 2012;19:1325– 1331 3.
  41. Berger D, et al. Efficacy of Vitex agnus-castus L. extract Ze 440 in patients with pre-menstrual syndrome (PMS). Arch Gynecol. Obstet. 2000;264:150-153.
  42. Koetter U, et al. A randomized, double blind, placebo-controlled, prospective clinical study to demonstrate clinical efficacy of a fixed valerian hops extract combination (Ze 91019) in patients suffering from non-organic sleep disorder. Phytother Res 2007;21(9):847-51.
  43. Notter D, et al. Efficacy and safety of a valerian-hops combination-preparation in different sleep disorders, a therapy observation. Phytotherapy. 2003;3:9-13.
  44. Füssel A, et al. Effect of a fixed valerian-hop extract combination (Ze 91019) on sleep polygraphy in patients with non-organic insomnia: a pilot study. Eur J Med Res. 2000;5:385–90.
  45. Lataster MJ, et al. The treatment of patients with sleep disorders. Notabene Medici. 1996;4:182.
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  48. Brattstrom A. Long-term effects of St. John’s wort (Hypericum perforatum) treatment: A 1-year safety study in mild to moderate depression. Phytomedicine 2009;16:277-83.
  49. Schrader E. Equivalence of St John’s wort extract (Ze 117) and fluoxetine: a randomized, controlled study in mild-moderate depression. Int Clin Psychopharmacol. 2000;15:61-8.
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